Towards the Replacement of in vivo Repeated Dose Systemic Toxicity Testing
| Knowledge Source Identification | |
|---|---|
| Knowledge source name | Towards the Replacement of in vivo Repeated Dose Systemic Toxicity Testing |
| Owner/Developer | SEURAT-1 |
| Country | Belgium |
| Languages | English |
| URL | http://www.seurat-1.eu/pages/library/seurat-1-annual-reports.php |
| Description | The SEURAT-1 research initiative will publish a series of six Annual Reports. These Annual Reports provide a comprehensive overview about developments ultimately targeting the replacement of animal tests in the field of repeated dose systemic toxicity assessment. These books called "Towards the replacement of in vivo repeated dose systemic toxicity testing", aim to inform policy makers about scientific progress relevant to the implementation of European Directives and Regulations and about essential gaps in knowledge corresponding to research needs. |
| Knowledge Source Category | |
| Category | Publication |
| Sub categories | Book / Textbook, Report |
| Knowledge Dissemination and Sharing | |
| Dissemination channel | Website, Printed |
| Targeted audience (specified/objective analysis) | Scientists, Regulators, Industry, Researchers |
| Users access | Open access |
| Knowledge Characterization | |
| 3Rs relevance | Replacement |
| Purpose | Method development, Documentation and information, Regulatory testing, Toxicological and safety evaluation |
| Legislative framework | Cosmetics Regulation (EC) No 1223/2009, REACH Regulation (EC) No 1907/2006, CLP Regulation (EC) No 1272/2008 |
| Technology/Tools | Alternative test methods (in vitro), Non-testing methods (in silico), Stem cells, Omics, Integrated approaches to testing and assessment (IATA), High throughput screening, High content screening, Analytics |