European Union Reference Laboratory for Alternatives to Animal Testing

Knowledge Source Identification
Knowledge source name European Union Reference Laboratory for Alternatives to Animal Testing
Abbreviated name EURL ECVAM
Owner/Developer European Commission, Joint Research Centre
Abbreviated owner EC - JRC
Country Italy
Languages English
Description The European Union Reference Laboratory for alternatives to animal testing (EURL-ECVAM) has been formally established in 2011, due to the increasing need for new methods to be developed and proposed for validation in the European Union. EURL ECVAM is hosted by the Joint Research Centre, Institute for Health and Consumer Protection (IHCP) located in Ispra, Italy. EURL ECVAM has a long tradition in the validation of methods which reduce, refine or replace the use of animals for safety testing and efficacy/potency testing of chemicals, biologicals and vaccines. Research laboratories are able to submit to EURL ECVAM for scientific validation the alternative methods to animal testing that they have developed. EURL ECVAM also promotes the development and dissemination of alternative methods and approaches, their application in industry and their acceptance by regulators. EU-NETVAL coordinator.
Knowledge Source Category
Category Organization
Sub categories Governmental Organization, ThreeRs Centre
Knowledge Dissemination and Sharing
Dissemination channel Face-to-face, Website, Audio / Video, Social media
Targeted audience (specified/objective analysis) Scientists, Regulators, Industry, Researchers
Users access Open access
Knowledge Characterization
3Rs relevance Replacement, Reduction, Refinement
Purpose Regulatory testing, Validation, Method development, Education and training, Documentation and information
Legislative framework Directive 2010/63/EU, Cosmetics Regulation (EC) No 1223/2009, REACH Regulation (EC) No 1907/2006
Technology/Tools Alternative test methods (in vitro), Non-testing methods (in silico), Integrated approaches to testing and assessment (IATA), High content screening, High throughput screening