GUIDANCE ON A STRATEGY FOR GENOTOXICITY TESTING

Knowledge Source Identification
Knowledge source name GUIDANCE ON A STRATEGY FOR GENOTOXICITY TESTING
Owner/Developer The Committee on Mutagenicity of Chemicals in Food, Consumer Products and the Environment
Abbreviated owner COM
Country United Kingdom
Languages English
URL https://www.gov.uk/government/uploads/system/uploads/attachment_data/file/315800/in_vivo_testing_of_genotoxicity_of_chemicals.pdf
Description The Committee on Mutagenicity of Chemicals in Food, Consumer Products and the Environment (COM) has a remit to provide UK Government Departments and Agencies with advice on the most suitable approaches to testing chemical substances for genotoxicity. The COM published guidance in 1981, 1989 and again in 2000. This document, incorporating some significant changes, reports on the COM views regarding the most appropriate strategy for genotoxicity testing reached in 2011.
Knowledge Source Category
Category Publication
Sub categories Guidance document
Knowledge Dissemination and Sharing
Dissemination channel Website
Targeted audience (specified/objective analysis) Regulators
Users access Open access
Knowledge Characterization
3Rs relevance Replacement, Reduction, Refinement
Purpose Toxicological and safety evaluation, Documentation and information
Technology/Tools Alternative test methods (in vitro), Animal testing (in vivo)