Alternatives to Animal Testing: A Review of Trends and Perspectives

Knowledge Source Identification
Knowledge source name Alternatives to Animal Testing: A Review of Trends and Perspectives
Owner/Developer Cosmetics&Toiletries Science Applied
Country United States of America
Languages English
Description For years, progress has been made in developing alternatives to animal testing as society has internationally sought methods to that end. Regulatory mandates have played a key role as well; the 7th Amendment to the Cosmetic Directive (2003/15/EC) was adopted by European Union (EU) institutions in 2003 and imposes strict deadlines to abolish in vivo animal studies for cosmetic ingredient testing. The other crucial regulation pressing for alternative methods is REACH, which was adopted by the European Council and the European Parliament in December 2006. It is worth mentioning that the ban on the testing of chemicals on animals refers strictly to compliance with requirements of the Cosmetic Directive. [...] Alternative test methods have the potential to reduce animal testing; however, the extent to which in vitro methods can be replaced is questionable. This article summarizes validated alternatives to test the safety of cosmetic ingredients. It also illustrates how great a challenge it is to devise a proper alternative method.
Knowledge Source Category
Category Publication
Sub categories Review / Research article
Knowledge Dissemination and Sharing
Dissemination channel Website
Targeted audience (specified/objective analysis) Scientists, Regulators, Industry, Researchers
Users access Open access, User registration
Knowledge Characterization
3Rs relevance Replacement
Purpose Documentation and information, Regulatory testing, Toxicological and safety evaluation
Legislative framework REACH Regulation (EC) No 1907/2006, Cosmetics Regulation (EC) No 1223/2009