NCI-60 Human Tumor Cell Lines Screen
| Knowledge Source Identification | |
|---|---|
| Knowledge source name | NCI-60 Human Tumor Cell Lines Screen |
| Abbreviated name | NCI-60 |
| Owner/Developer | National Cancer Institute |
| Abbreviated owner | NCI |
| Country | United States of America |
| Languages | English |
| URL | https://dtp.cancer.gov/discovery_development/nci-60/ |
| Description | The NCI-60 Human Tumor Cell Lines Screen has served the global cancer research community for >20 years. The screen was implemented in fully operational form in 1990 and utilizes 60 different human tumor cell lines to identify and characterize novel compounds with growth inhibition or killing of tumor cell lines. It is designed to screen up to 3,000 small molecules (synthetic or purified natural products) per year for potential anticancer activity. The operation of this screen utilizes 60 different human tumor cell lines, representing leukemia, melanoma and cancers of the lung, colon, brain, ovary, breast, prostate, and kidney cancers. |
| Knowledge Source Category | |
| Category | Information System |
| Sub categories | Database |
| Knowledge Dissemination and Sharing | |
| Dissemination channel | Website |
| Targeted audience (specified/objective analysis) | Researchers |
| Users access | Open access |
| Knowledge Characterization | |
| 3Rs relevance | Reduction, Replacement |
| Purpose | Documentation and information |
| Technology/Tools | Alternative test methods (in vitro) |