Toxicity Forecasting

Knowledge Source Identification
Knowledge source name Toxicity Forecasting
Abbreviated name ToxCast
Owner/Developer US Environmental Protection Agency
Abbreviated owner US EPA
Country United States of America
Languages English
Contact email
Description Advancing the Next Generation of Chemical Evaluation: EPA needs rapid and efficient methods to prioritize, screen and evaluate thousands of chemicals. EPA's Toxicity Forecaster (ToxCast) generates data and predictive models on thousands of chemicals of interest to the EPA. ToxCast uses high-throughput screening methods and computational toxicology approaches to rank and prioritize chemicals. In fact, EPA's Endocrine Disruption Screening Program (EDSP) is working to use ToxCast to rank and prioritize chemicals. As part of EPA’s commitment to gather and share its chemical data in open and transparent ways, all ToxCast chemical data is publicly available.
Knowledge Source Category
Category Research Program/Project/Grant
Sub categories National / Regional Program
Knowledge Dissemination and Sharing
Dissemination channel Website, Audio / Video, Social media, Professional online network
Targeted audience (specified/objective analysis) Scientists, Regulators, Industry
Users access Open access
Knowledge Characterization
3Rs relevance Replacement, Reduction
Purpose Regulatory testing, Toxicological and safety evaluation, Documentation and information
Technology/Tools High throughput screening, High content screening, Omics, Alternative test methods (in vitro)