Stem cells for relevant efficient extended and normalized toxicology
| Knowledge Source Identification | |
|---|---|
| Knowledge source name | Stem cells for relevant efficient extended and normalized toxicology |
| Abbreviated name | SCR&Tox |
| Owner/Developer | European Commission and Cosmetics Europe |
| Country | France |
| Languages | English |
| URL | http://www.scrtox.eu/ |
| Contact | http://www.scrtox.eu/index.php?option=com_content&view=article&id=17&Itemid=6 |
| Description | In the development of products for use by humans it is vital to identify compounds with toxic properties at an early stage of their development, to avoid spending time and resource on unsuitable and potentially unsafe candidate products. Human pluripotent stem cell lines offer a unique opportunity to develop a wide variety of human cell-based test systems because they may be expanded indefinitely and triggered to differentiate into any cell type. SCR&Tox aims at making use of these two attributes to provide in vitro assays for predicting toxicity of pharmaceutical compounds and cosmetic ingredients. The consortium has been designed to address all issues related with biological and technological resources to meet that goal. |
| Knowledge Source Category | |
| Category | Research Program/Project/Grant |
| Sub categories | EU Program |
| Knowledge Dissemination and Sharing | |
| Dissemination channel | Face-to-face, Website, Social media, Printed |
| Targeted audience (specified/objective analysis) | Scientists, Regulators, Industry, Researchers |
| Users access | Open access |
| Knowledge Characterization | |
| 3Rs relevance | Replacement |
| Purpose | Regulatory testing, Toxicological and safety evaluation, Method development, Documentation and information |
| Technology/Tools | Alternative test methods (in vitro), Stem cells |