Safety Evaluation Ultimately Replacing Animal Testing

Knowledge Source Identification
Knowledge source name Safety Evaluation Ultimately Replacing Animal Testing
Abbreviated name SEURAT-1
Owner/Developer European Commission and Cosmetics Europe
Country Belgium
Languages English
Description The goal of the 5-year SEURAT-1 Research Initiative ('Towards the replacement of in vivo repeated dose systemic toxicity testing') was to develop a consistent research strategy ready for implementation in following research programmes. This includes establishing innovative scientific tools for better understanding of repeated dose toxicity based on in vitro tests, and identifies gaps of knowledge to be bridged by future research work. The end result would be testing methods which, within the framework of safety assessment, have a higher predictive value, are faster and cheaper than those currently used, and significantly reduce the use of animal tests.
Knowledge Source Category
Category Research Program/Project/Grant
Sub categories EU Program
Knowledge Dissemination and Sharing
Dissemination channel Face-to-face, Website, Audio / Video, Social media, Printed
Targeted audience (specified/objective analysis) Scientists, Industry, Researchers, Regulators
Users access Open access
Knowledge Characterization
3Rs relevance Replacement
Purpose Regulatory testing, Toxicological and safety evaluation, Method development, Education and training, Documentation and information
Legislative framework Cosmetics Regulation (EC) No 1223/2009, REACH Regulation (EC) No 1907/2006
Technology/Tools Alternative test methods (in vitro), Non-testing methods (in silico), Stem cells, Omics, Integrated approaches to testing and assessment (IATA), High throughput screening, High content screening, Analytics