In Vitro Toxicology Systems

Knowledge Source Identification
Knowledge source name In Vitro Toxicology Systems
Owner/Developer Springer Science+Business Media New York
Country United States of America
Languages English
Description In Vitro Toxicology Systems brings together important issues and considerations needed in order to develop a workable, reliable, integrated testing strategy for the replacement of animals in toxicity testing regimes. This thorough volume includes sections on in vitro models for systemic organ toxicity, neurotoxicity, sensory organs, immunotoxicity and reproductive toxicity and addresses how stem cells may be used going forward. The book also tackles difficult areas of toxicology such as carcinogenicity and nanotoxicology, with additional chapters dedicated to kinetics, metabolism, and in vitro in vivo extrapolation. The book also addresses biological processes such as stress response pathways and mechanistic biomarkers and how these can be uncovered and measured using high content approaches. Reliable and authoritative, In Vitro Toxicology Systems will be of benefit not only to students, scientists and regulators working in the field of chemical safety assessment but also to a wider scientific audience.
Knowledge Source Category
Category Publication
Sub categories Book / Textbook
Knowledge Dissemination and Sharing
Dissemination channel Website, Printed
Targeted audience (specified/objective analysis) Students, Scientists, Regulators, Researchers
Users access Fee-based access
Knowledge Characterization
3Rs relevance Replacement
Purpose Toxicological and safety evaluation, Method development, Education and training, Documentation and information
Technology/Tools Stem cells, Tissue engineering, Alternative test methods (in vitro)