Toxicology in Vitro

Knowledge Source Identification
Knowledge source name Toxicology in Vitro
Abbreviated name TiV
Owner/Developer Elsevier Ltd.
Abbreviated owner ESTIV
Country Netherlands
Languages English
Description Affiliated with the American Association for Cellular and Computational Toxicology, European Society for Toxicology in Vitro. Toxicology in Vitro publishes original research papers and reviews on the application and use of in vitro systems for assessing or predicting the toxic effects of chemicals and elucidating their mechanisms of action. These in vitro techniques include utilizing cell or tissue cultures, isolated cells, tissue slices, subcellular fractions, transgenic cell cultures, and cells from transgenic organisms, as well as in silico modelling. The Journal will focus on investigations that involve the development and validation of new in vitro methods, e.g. for prediction of toxic effects based on traditional and in silico modelling; on the use of methods in high-throughput toxicology and pharmacology; elucidation of mechanisms of toxic action; the application of genomics, transcriptomics and proteomics in toxicology, as well as on comparative studies that characterise the relationship between in vitro and in vivo findings.
Knowledge Source Category
Category Publication
Sub categories Journal
Knowledge Dissemination and Sharing
Dissemination channel Website, E-mail, Printed
Targeted audience (specified/objective analysis) Not specified
Users access Open access, Restricted access
Knowledge Characterization
3Rs relevance Replacement, Reduction
Purpose Regulatory testing, Toxicological and safety evaluation, Method development, Validation, Documentation and information
Technology/Tools High throughput screening, Non-testing methods (in silico), Omics, Alternative test methods (in vitro)