Systematic Review Centre for Laboratory animal Experimentation

Knowledge Source Identification
Knowledge source name Systematic Review Centre for Laboratory animal Experimentation
Abbreviated name SYRCLE
Owner/Developer Radboud University Medical Center
Country Netherlands
Languages Dutch, English
Contact email
Description SYRCLE is the research and education centre of the Central Animal Laboratory (CDL) of the Radboud University Medical Center. Systematic Review (SR) is the methodological approach SYRCLE has adopted for the Syntheses of Evidence (SE). SYRCLE (SYstematic Review Centre for Laboratory animal Experimentation) was officially founded in 2012. Already in 2008/2009 the research staff had shifted their focus from the 3Rs towards the execution of systematic reviews (SR), because these are a method to identify, appraise, select and synthesise all available research results. SRs help to improve scientific quality, facilitate the implementation of the 3Rs and –last but not least- aid in securing patient safety. SYRCLE focuses on the execution of SRs of animal studies towards more evidence-based translational medicine. To this effect SYRCLE developes education, methodological tools and guidelines, organizes workshops and coaches individuals wishing to perform a SR themselves.
Knowledge Source Category
Category Organization
Sub categories Academia, Services
Knowledge Dissemination and Sharing
Dissemination channel Website
Targeted audience (specified/objective analysis) Scientists, Researchers
Users access Open access
Knowledge Characterization
3Rs relevance Replacement, Reduction, Refinement
Purpose Animal welfare, Education and training, Documentation and information