Prolonged Pain Research in Mice: Trends in Reference to the 3Rs

Knowledge Source Identification
Knowledge source name Prolonged Pain Research in Mice: Trends in Reference to the 3Rs
Owner/Developer Journal of Applied Animal Welfare Science
Country United Kingdom
Languages English
URL http://www.tandfonline.com/doi/abs/10.1080/10888705.2013.741004?tab=permissions&scroll=top
Description This literature review documents trends in the use of mice in prolonged pain research, defined herein as research that subjects mice to a source of pain for at least 14 days. The total amount of prolonged pain research on mice has increased dramatically in the past decade for the 3 pain categories examined: neuropathic, inflammatory, and chronic pain. [...] Finally, although most authors referred to approval of experiments by an institutional nonhuman animal use committee, there were no references to the “3Rs” in a random selection of 55 papers examined.
Knowledge Source Category
Category Information System
Sub categories Review / Research article
Knowledge Dissemination and Sharing
Dissemination channel Website
Targeted audience (specified/objective analysis) Scientists, Researchers
Users access Restricted access
Knowledge Characterization
3Rs relevance Replacement, Reduction, Refinement
Purpose Documentation and information
Technology/Tools Animal testing (in vivo)