Prolonged Pain Research in Mice: Trends in Reference to the 3Rs

Knowledge Source Identification
Knowledge source name Prolonged Pain Research in Mice: Trends in Reference to the 3Rs
Owner/Developer Journal of Applied Animal Welfare Science
Country United Kingdom
Languages English
Description This literature review documents trends in the use of mice in prolonged pain research, defined herein as research that subjects mice to a source of pain for at least 14 days. The total amount of prolonged pain research on mice has increased dramatically in the past decade for the 3 pain categories examined: neuropathic, inflammatory, and chronic pain. [...] Finally, although most authors referred to approval of experiments by an institutional nonhuman animal use committee, there were no references to the “3Rs” in a random selection of 55 papers examined.
Knowledge Source Category
Category Information System
Sub categories Review / Research article
Knowledge Dissemination and Sharing
Dissemination channel Website
Targeted audience (specified/objective analysis) Scientists, Researchers
Users access Restricted access
Knowledge Characterization
3Rs relevance Replacement, Reduction, Refinement
Purpose Documentation and information
Technology/Tools Animal testing (in vivo)