ToxFX

Knowledge Source Identification
Knowledge source name ToxFX
Owner/Developer U.S. Department of Health and Human Services, National Toxicology Program
Abbreviated owner NTP
Country United States of America
Languages English
URL https://ntp.niehs.nih.gov/toxfx/
Contact email toxfx@niehs.nih.gov
Description ToxFX is an automated toxicogenomics analysis application. The ToxFX analytical approach utilizes toxicogenomic signatures, specially-curated biochemical pathways and other relevant data to interpret toxicity-related transcriptomic data in minutes and presents the results as a detailed, customized report. The ToxFX report can be produced from data generated from either Affymetrix GeneChip® Rat Genome 230 2.0 arrays or reduced feature set Affymetrix GeneChip® Rat ToxFX 1.0 arrays. The ToxFX 1.0 array contains customized content based on the NTP DrugMatrix® reference database. All that is required for data upload is PLIER normalized .chp files.
Knowledge Source Category
Category Information System
Sub categories Online tool / Search engine
Knowledge Dissemination and Sharing
Dissemination channel Website
Targeted audience (specified/objective analysis) Not specified
Users access Open access, User registration
Knowledge Characterization
3Rs relevance Replacement, Reduction
Purpose Documentation and information
Technology/Tools Omics