Knowledge Source Identification
Knowledge source name ToxFX
Owner/Developer U.S. Department of Health and Human Services, National Toxicology Program
Abbreviated owner NTP
Country United States of America
Languages English
Contact email
Description ToxFX is an automated toxicogenomics analysis application. The ToxFX analytical approach utilizes toxicogenomic signatures, specially-curated biochemical pathways and other relevant data to interpret toxicity-related transcriptomic data in minutes and presents the results as a detailed, customized report. The ToxFX report can be produced from data generated from either Affymetrix GeneChip® Rat Genome 230 2.0 arrays or reduced feature set Affymetrix GeneChip® Rat ToxFX 1.0 arrays. The ToxFX 1.0 array contains customized content based on the NTP DrugMatrix® reference database. All that is required for data upload is PLIER normalized .chp files.
Knowledge Source Category
Category Information System
Sub categories Online tool / Search engine
Knowledge Dissemination and Sharing
Dissemination channel Website
Targeted audience (specified/objective analysis) Not specified
Users access Open access, User registration
Knowledge Characterization
3Rs relevance Replacement, Reduction
Purpose Documentation and information
Technology/Tools Omics