Profiling the toxicity of new drugs: a non animal-based approach integrating toxicodynamics and biokinetics
| Knowledge Source Identification | |
|---|---|
| Knowledge source name | Profiling the toxicity of new drugs: a non animal-based approach integrating toxicodynamics and biokinetics |
| Abbreviated name | Predict-IV |
| Owner/Developer | European Commission |
| Abbreviated owner | EC |
| Country | Germany |
| Languages | English |
| URL | http://www.predict-iv.toxi.uni-wuerzburg.de/startseite/ |
| Description | The overall aim of Predict-IV was to develop strategies to improve the assessment of drug safety in the early stage of development and late discovery phase, by an intelligent combination of non animal-based test systems, cell biology, mechanistic toxicology and in-silico modelling, in a rapid and cost effective manner. |
| Knowledge Source Category | |
| Category | Research Program/Project/Grant |
| Sub categories | EU Program |
| Knowledge Dissemination and Sharing | |
| Dissemination channel | Website |
| Targeted audience (specified/objective analysis) | Scientists, Industry, Researchers |
| Users access | Open access |
| Knowledge Characterization | |
| 3Rs relevance | Replacement, Reduction, Refinement |
| Purpose | Toxicological and safety evaluation, Regulatory testing, Method development |
| Legislative framework | Medicines legislation |
| Technology/Tools | Alternative test methods (in vitro), Non-testing methods (in silico), Omics |