Prolonged Pain Research in Mice: Trends in Reference to the 3Rs
Knowledge Source Identification | |
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Knowledge source name | Prolonged Pain Research in Mice: Trends in Reference to the 3Rs |
Owner/Developer | Journal of Applied Animal Welfare Science |
Country | United Kingdom |
Languages | English |
URL | http://www.tandfonline.com/doi/abs/10.1080/10888705.2013.741004?tab=permissions&scroll=top |
Description | This literature review documents trends in the use of mice in prolonged pain research, defined herein as research that subjects mice to a source of pain for at least 14 days. The total amount of prolonged pain research on mice has increased dramatically in the past decade for the 3 pain categories examined: neuropathic, inflammatory, and chronic pain. [...] Finally, although most authors referred to approval of experiments by an institutional nonhuman animal use committee, there were no references to the “3Rs” in a random selection of 55 papers examined. |
Knowledge Source Category | |
Category | Information System |
Sub categories | Review / Research article |
Knowledge Dissemination and Sharing | |
Dissemination channel | Website |
Targeted audience (specified/objective analysis) | Scientists, Researchers |
Users access | Restricted access |
Knowledge Characterization | |
3Rs relevance | Replacement, Reduction, Refinement |
Purpose | Documentation and information |
Technology/Tools | Animal testing (in vivo) |